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Influenza Immunization in Adults Over Age 75

RecruitingNAAges 75 Years - anyAllJohns Hopkins University
NCT02200276 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The immune system is the part of the body that protects against infection. The immune system often doesn't work as effectively as people get older. This research is being done to find out how the immune systems in older people who are over age 75 respond to influenza vaccine (flu shot). We also want to find out if chronic cytomegalovirus (CMV) infection, a common virus infection in older persons affects the immune response in people older than 75 years of age who receive a flu shot. The Flu Shot is a vaccine approved for the prevention of influenza ("Flu") infections and is recommended every year for all persons 50 years and older. People who are older than 75 years of age are considered healthy or frail may join. A total of 1025 persons will be participating in this study. In order to determine if you are qualified for the study, we would ask you to answer a few questions over the phon

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults over age 75 years Exclusion Criteria: * Allergies to egg or vaccine * Active malignancies * On radiation or chemotherapy * Active systemic inflammatory diseases including rheumatoid arthritis, Crohn's disease, and ulcerative colitis * Acute exacerbation of chronic cardiopulmonary conditions including decompensated CHF or COPD * Taking oral steroids (such as prednisone) or immune modulating drugs (such as methotrexate). * Lacking the capacity to consent (individuals who do not understand what Flu shot is or need someone else to decide if s/he should get the Flu shot)
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What it tests

  • Influenza
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Where

1 site
Johns Hopkins University; JHAAC 5501 Hopkins Bayview Circle, 1B84
Baltimore, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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