🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Screening for Synchronous Metastases in Colorectal Cancer With DW-MRI (SERENADE)

RecruitingNAAges 16 Years - anyAllImperial College London
NCT02246634 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Eligible patients with high risk colorectal malignancy (T3/4, spread greater than 5mm, EMVI positive) will have additional surveillance of breath hold T1, T2 and DW-MRIs (no IV contrast) post surgery six monthly for three years. Findings of liver MRIs as reported by radiology PI will be shared with their local MDT who make decisions as appropriate, including the management of any identified liver metastases, according to local protocol.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: 1. Have a high risk primary colorectal malignancy 2. Have a negative CT or includes no confirmatory evidence of liver metastases 3. Is able to undergo treatment if liver metastasis is found 4. Have provided written informed consent to participate in the study 5. Be aged 16 years or over Exclusion Criteria: 1. Have had a previous colorectal malignancy 2. Have metastatic disease 3. Have a synchronous second malignancy 4. Are contraindicated for MRI 5. Has a T3b or below low rectal tumour without EMVI or N1c
💊

What it tests

  • Diffusion Weighted MRI scan
📍

Where

13 sites
Macclesfield District General Hospital
Macclesfield, United Kingdom
Queen's Hospital
Burton-on-Trent, United Kingdom
Broomfield Hospital
Chelmsford, United Kingdom
Royal Bolton Hospital
Bolton, United Kingdom
Medway Maritime Hospital
Gillingham, United Kingdom
University Hospital of South Manchester & Manchester Royal Infirmary
Wythenshawe, United Kingdom
Royal Liverpool Hospital
Liverpool, United Kingdom
Royal Stoke University Hospital
Stoke-on-Trent, United Kingdom

…and 5 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy