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← Trials
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Safety and Durability of Sirolimus for Treatment of LAM

Recruitingn/aAges 18 Years - anyFemaleUniversity of Cincinnati
NCT02432560 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The MIDAS study aims to follow male and female LAM patients who are currently taking, have previously failed or been intolerant of, or may (at some time in the future) take mTOR inhibitors (sirolimus or everolimus) as part of their clinical care. Adult female TSC patients may also enroll, with or without lung cysts.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Female or male, age 18 or over * Diagnosis of LAM based on ATS/JRS criteria * Signed and dated informed consent * On chronic therapy, newly treated or may be considered for therapy with mTOR inhibitors or previously intolerant of or having failed mTOR inhibitor therapy Exclusion Criteria: * Inability to attend at least one RLD Clinic visit per year * Inability to give informed consent * Inability or unwillingness to perform pulmonary function testing
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What it tests

  • Sirolimus
  • Everolimus
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Where

20 sites
Stanford University Medical Center
Stanford, United States
National Jewish Health
Denver, United States
Mayo Clinic Jacksonville
Jacksonville, United States
Emory University School of Medicine
Atlanta, United States
Loyola University Medical Center, Chicago
Maywood, United States
Brigham and Women's Hospital
Boston, United States
University of Michigan
Ann Arbor, United States
Mayo Clinic Rochester
Rochester, United States

…and 12 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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