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Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk

Recruitingn/aAges 18 Years - anyAllAbramson Cancer Center at Penn Medicine
NCT02478892 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The study is a prospective, observational study evaluating the utility of endoscopic ultrasound or MRI for the identification of preneoplastic and neoplastic pancreatic lesions in patients at high risk for pancreatic cancer, specifically those with BRCA1/2, ATM, or PALB2 mutations.

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📋 Eligibility rules (as published)
Inclusion Criteria * Age \>= 18 * Documented germline pathogenic or likely pathogenic BRCA1, BRCA2, ATM, or PALB2 mutation * If no history of PDAC in a first or second degree relative, age \>= 50 * If there is a history of PDAC in a first or second degree relative, minimum age of eligibility is 10 years younger than the age of onset of the youngest relative with pancreatic cancer Exclusion Criteria • Pregnancy
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What it tests

  • Collection of data from endoscopic ultrasound or MRI/MRCP of the abdomen
  • Blood sample collection for research
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Where

1 site
Abramson Cancer Center of the University of Pennsylvania
Philadelphia, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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