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Habituation's Mechanisms in Preterm and Term Infants

Recruitingn/aAges 2 Days - 10 WeeksAllUniversity Hospital, Brest
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In plain words

What the trial is, and whether it could suit you

Each year in France, 7 % of newborns are born preterm (before 37 weeks of gestational age (GA)). The investigators called very preterm infants those who were born before 33 weeks of GA. These very preterm infants have a higher risk of developing neurological complications like developmental disabilities or cerebral palsy. To date, early assessment of these infants is difficult and not reliable enough to detect those who are at risks of developing neurological issues. Now, the investigators need to identify earlier these infants to provide them interventions to improve their development (physical therapy for example). Consequently, the investigators are examining a study whose aim is to assess preterm infants habituation. Habituation is the newborn ability to become familiar with new environmental stimulations (noise, lightโ€ฆ). This habituation allows the newborn to maintain his sleep even

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Preterm infants: preterm infants born from 25 weeks to 32 weeks + 6 days of gestation near to 36 weeks of gestation (corrected postnatal age) * Term infants: term newborns with a gestational age between 39 and 41 weeks of gestation at day 3 with an Apgar โ‰ฅ 1 at 1 minute of life * For both groups: normal neurological physical examination, written informed consent of the parents Exclusion Criteria: * no malformation or chromosomal abnormality, life threatening disease, administration of morphine or sedatives during the 24 hours before the study, context of maternal drug addiction, deafness, no psychoactive drug or anticonvulsivants during the last month of pregnancy for the term newborns, severe neurological disease
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What it tests

  • Package nยฐ1 of the APIB
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Where

1 site
CHRU de Brest
Brest, France
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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