AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

OMEGA: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages

Recruitingn/aAges 3 Years - anyAllChildren's Hospital Medical Center, Cincinnati
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

The purpose of this observational study is to find the best measures to define how well a person with eosinophilic disorder is doing. People with EoE, EoG, EoN and EoC normally undergo endoscopy and/or colonoscopy where cells are collected for microscopic analysis. Treatments are then decided based on how the cells look. We are aiming to compare different tissue components such as inflammatory cell types with clinical symptoms. We want to see if scores on standard questionnaires can give us an idea how well the person is doing.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Males or females 3 years of age and older * Mucosal eosinophilia: EoE โ‰ฅ 15 eosinophils/HPF in the distal or proximal esophagus EoG โ‰ฅ 30 eosinophils/HPF in 5 HPF\'s in the body and/or antrum EoN โ‰ฅ 53 eosinophils/HPF in the duodenum and/or โ‰ฅ 56 eosinophils/HPF in the jejunum and/or ileum EoC โ‰ฅ 84 eosinophils/HPF from the transverse or descending colon and/or โ‰ฅ 32 eosinophils/HPF from the rectosigmoid colon or a biopsy from any colonic location with โ‰ฅ 100 eosinophils/HPF \- Presence of symptoms is required for patients who are newly diagnosed but not required for patients who were previously diagnosed. Exclusion Criteria: * History of intestinal surgery other than G tube placement * Enrolled in a blinded investigational study at the time of the first study visit * Have esophageal stricture (\<3mm) * Have other identifiable causes for eosinophilia (except Inflammatory Bowel Disease): infections, Gastrointestinal (GI) cancer, other GI inflammatory disease (e.g., Ulcerative Colitis or Crohn\'s Disease)
๐Ÿ’Š

What it tests

  • Not listed
๐Ÿ“

Where

19 sites
Mayo Clinic Hospital
Phoenix, United States
Arkansas Children's Research Institute
Rogers, United States
Rady Children's Hospital
San Diego, United States
University of Colorado Denver
Aurora, United States
Children's Hospital Colorado
Denver, United States
Northwestern University
Chicago, United States
Ann and Robert H. Lurie Children's Hospital of Chicago
Chicago, United States
Riley Children's Hospital
Indianapolis, United States

โ€ฆand 11 more on ClinicalTrials.gov.

๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy