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Rod and Cone Mediated Function in Retinal Disease

Recruitingn/aAges 5 Years - 100 YearsAllNational Eye Institute (NEI)
NCT02617966 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Background: Retinal diseases cause the loss of rod and cone photoreceptors. Symptoms include vision loss and night blindness. Researchers want to learn about rod and cone function in healthy people and people with retinal disease. They want to know if how well a person sees in the dark can test the severity of retinal disease. Objectives: To find out if how well a person sees in the dark can test the severity of retinal disease. To find out if this can help detect retinal disease and track its changes. Eligibility: People ages 5 and older with: Retinal disease OR 20/20 vision or better with or without correction in at least one eye Design: Participants will be screened with medical and eye history and eye exam. Those with retinal disease will also have: Eye imaging: Drops dilate the eye and pictures are taken of it. Visual field testing: Participants look into a bowl and press

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📋 Eligibility rules (as published)
* INCLUSION CRITERIA: * Participant must be five years of age or older. * Participant (or legal guardian) must understand and sign the protocol s informed consent document. * Participant must be able to cooperate with the testing required for this study. For Participants with retinal disease only: * Participant must have retinal disease, defined as evidence of loss of retinal dysfunction and/or degeneration as established by standard clinical methods including perimetry, ERG and imaging. * Participant must have a measurable visual acuity. For Healthy Volunteers only: -Participant must have visual acuity of 20/20 or better, with or without correction (e.g., glasses or contact lens) in at least one eye. EXCLUSION CRITERIA: -Participant with changes in pre-retinal media sufficient to obscure a view of the retina.
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What it tests

  • Not listed
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Where

1 site
National Institutes of Health Clinical Center
Bethesda, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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