🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Loop Diuretic Therapy in Acutely Decompensated Heart Failure

Recruitingn/aAges 18 Years - anyAllUniversity of Siena
NCT02638142 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

DiurHF is a prospective, multicenter, observational, study that compares continuous with intermittent infusion of furosemide in patients admitted with a diagnosis of ADHF. Previous pilot study design was planned to anticipate a larger multicenter trial able to definitively evaluate the optimal loop diuretic use strategy in patients with ADHF.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Patients over 18 years; * Patients with diagnosis of ADHF(dyspnea, orthopnea, peripheral edema or major fatigue and at least two clinical signs including rales, hepatomegaly, pulmonary congestion on chest radiography, jugular vein dilatation, or a third heart sound); * Blood BNP \> 100 pg/mL; ADHF: Acute Decompensated Heart Failure; BNP: B-type Natriuretic Peptide; IV: IntraVenous; LVEF: Left Ventricular Ejection Fraction. Exclusion Criteria: * Patients who receive more than 40 mg of IV furosemide; * End-Stage renal disease or renal replacement therapy; * Recent myocardial infarction (within thirty days of screening); * Systolic blood pressure \< 80 mmHg; * Creatinine levels \> 4 mg/dL; * Patients affected by sepsis, liver diseases, inflammatory diseases or neoplastic diseases.
💊

What it tests

  • Continuous Furosemide Infusion
  • Intermittent Furosemide Infusion
📍

Where

4 sites
Ospedale Madonna della Navicella
Chioggia, Italy
Azienda Ospedaliera di Padova
Padova, Italy
University of Rome La Sapienza
Roma, Italy
Department of Internal Medicine, Cardiovascular Diseases Unit
Siena, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy