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Molecular, Cellular, and Genetic Characterization of Human Adipose Tissue and Its Role in Metabolism

Recruitingn/aAges 18 Years - 90 YearsAllNational Institute of Diabetes and Digestive and …
NCT02692885 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Background: The body uses energy from calories for basic functions like breathing and digesting food. Over time, when a person eats more calories than they burn, they may become overweight or obese. Obesity is a major health concern. Researchers want to look at fat and muscle tissue to learn more about metabolism. That is how the body uses food and other nutrients for normal function and energy. This research may help to develop new treatments for obesity and related diseases. Objective: To learn more about the role of fat and muscle in metabolism, particularly how fat and muscle store and use energy. Eligibility: Adults 18 years and older who have a planned surgery at NIH in which tissue can be collected by the surgeon. Design: Participants will be screened by their regular NIH doctor. Then researchers will contact them about this study. Participants will not have to make extra

Sign in to get the eligibility rules as simple questions to take to your doctor.

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📋 Eligibility rules (as published)
* INCLUSION/EXCLUSION CRITERIA FOR SUBJECTS UNDERGOING SURGERY (COHORT 1) INCLUSION CRITERIA: * Male or female * Any ethnicity * 18 years or older * Subject undergoing planned, clinically-indicated surgical procedure at the NIH Clinical Center in which tissue will be accessible and available for collection by the Operating Surgeon. EXCLUSION CRITERIA: * Inability to provide consent. * Pregnancy INCLUSION/EXCLUSION CRITERIA FOR ALL OTHER SUBJECTS (HEALTHY VOLUNTEERS AND NON-SURGICAL PATIENTS (COHORT 2): INCLUSION CRITERIA: * Male or female * Any ethnicity * 18-80 year * For supraclavicular or dorsocervical adipose biopsy: 18F-FDG PET/CT Scan images available in the CRC PACS system (performed as part of separate protocol) EXCLUSION CRITERIA: * History of keloids. * Currently taking blood thinning or anti-inflammatory medications including anti-platelet or antithrombotic medications. * Pregnancy * History of pacemaker, metallic heart valves, aneurysm clip, pedicle screws, metallic foreign body in eye, or other metallic implant only if using fusion technology for the biopsy procedure. * Psychological conditions including (but not limited to) clinical depression, bipolar disorders, or forms of mental incapacity that would be incompatible with safe and successful participation in this study. * Addiction to alcohol or substances of abuse within the last 5 years; current use of drugs or alcohol (CAGE greater than or equal to 2). * Inability to provide consent. All subjects will be fully informed of the aims, nature, and risks of the study prior to giving written informed consent.
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What it tests

  • Not listed
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Where

1 site
National Institutes of Health Clinical Center
Bethesda, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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