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Prospective Research Rare Kidney Stones (ProRKS)

Recruitingn/aAges any - anyAllMayo Clinic
NCT02780297 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to determine the natural history of the hereditary forms of nephrolithiasis and chronic kidney disease (CKD), primary hyperoxaluria (PH), cystinuria, Dent disease and adenine phosphoribosyltransferase deficiency (APRTd) and acquired enteric hyperoxaluria (EH). The investigator will measure blood and urinary markers of inflammation and determine relationship to the disease course. Cross-comparisons among the disorders will allow us to better evaluate mechanisms of renal dysfunction in these disorders.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Diagnosis of primary hyperoxaluria 2. Diagnosis of enteric hyperoxaluria 3. Diagnosis of Dent Disease 4. Diagnosis of Cystinuria 5. Diagnosis of adenine phosphoribosyltransferase deficiency (APRTd) 6. Diagnosis of Lowe Syndrome 7. Diagnosis of Dent Disease Carrier Exclusion Criteria: 1. Prior renal failure 2. History of liver and/or kidney transplant.
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What it tests

  • Not listed
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Where

11 sites
University of Alabama @ Birmingham
Birmingham, United States
Mayo Clinic Jacksonville
Jacksonville, United States
Children's Memorial Hospital
Chicago, United States
Children's Hospital, Harvard Medical School
Boston, United States
Mayo Clinic Hyperoxaluria Center
Rochester, United States
New York University
New York, United States
Cincinnati Children's Hosptial Medical Center
Cincinnati, United States
Children's Hospital of Philadelphia
Philadelphia, United States

…and 3 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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