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CTT on Renogram as an Early Marker of Significant Obstruction in Uretero-pelvic Junction Syndrome

RecruitingNAAges 4 Weeks - 8 WeeksAllCentre Hospitalier Universitaire de la Réunion
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In plain words

What the trial is, and whether it could suit you

Cortical transit time on diuretic renogram as an early marker of significant obstruction in antenatally detected uretero-pelvic junction syndrome

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📋 Eligibility rules (as published)
Inclusion Criteria: Infants: * Aged of 4 to 8 weeks of life * Presenting an ureteropelvic junction obstruction (UPJO) detected before birth by ultrasound * Presenting an UPJO, defined by an Antero-Posterior Renal Pelvic Diameter greater or equal to 15 mm, confirmed by ultrasound post-natally between the 1st and 15th day of life * Presenting a unilateral UPJO * whose legal representatives have provided a signed free and informed written consent for their infant's participation * whose at least one of his legal representative is affiliated to national social security Exclusion Criteria: Infants presenting: * A bilateral UPJO * An ureteral dilatation * An associated contralateral uropathy * A solitary kidney * A renal insufficiency * Severe associated disabilities ( ie polymalformation syndromes) * A concomitant participation in another trial * A contraindication to furosemide (acute renal insufficiency, hepatic encephalopathy, hypovolemia or dehydration, severe hypokalemia, severe hyponatremia) * A contraindication to the radionuclide marker (hypersensitivity to the active substance or to excipients)
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What it tests

  • ultrasonography
  • diuretic renography
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Where

5 sites
CHU de Bordeaux
Bordeaux, France
CHU de Limoges
Limoges, France
CHU de Nantes
Nantes, France
CHU de Rennes
Rennes, France
Centre Hospitalier Universitaire de La Réunion
Saint-Denis, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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