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A Randomised Trial of Chemotherapy Plus Surgery for Recurrent Non-Small Cell Lung Cancer

RecruitingPhase 1Ages 18 Years - 75 YearsAllShanghai Jiao Tong University School of Medicine
NCT02889666 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to determine if the commonly administered chemotherapeutic agents including cisplatin, carboplatin, oxaliplatin, docetaxel and gemcitabine for solid tumors in clinical oncology, either a single format or given as combinations followed by surgery are effective in the treatment of relapsed and refractory non-small cell lung cancer patients.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≤ 75 years with histologically proven NSCLC * No severe major organ dysfunction * WHO performance status of 0 or 1 * No prior cancer chemotherapy * A Clinical Stage ≥ IA (T1a, N0, M0) of lung disease but without diagnosed distant metastasis (according to the 1997 revision of the International Union Against Cancer TNM staging system) as determined by a preoperative evaluation that included a pleural computed tomography (CT) scan. Exclusion Criteria: * Age ≥ 76 * Severe major organ dysfunction * WHO performance status of \>1 * Prior cancer chemotherapy * Stage IV
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What it tests

  • Cisplatin
  • Carboplatin
  • Docetaxel
  • Gemcitabine/Carboplatin
  • Gemcitabine/Cisplatin
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Where

3 sites
China-Japan Union Hospital, Jilin University
Changchun, China
Shanghai 10th People's Hospital
Shanghai, China
Shanghai Pulmonary Hospital, Tongji University School of Medicine
Shanghai, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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