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Pulmonary Rehabilitation in Advanced Non-small Cell Lung Cancer Patients

RecruitingNAAges 18 Years - 70 YearsAllInstituto Nacional de Cancerologia de Mexico
NCT02978521 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Lung cancer (LC) is usually diagnosed in advanced stages and continues to be the leading cause of cancer related deaths worldwide. Cancer cachexia are frequent among patients with LC affecting up to 80% of patients with advanced stage disease, and it has been related with higher risk of complications, length of hospital stay, and worst overall survival. During cancer cachexia, both muscle and fat mass can be wasted, however, the loss of muscle mass has been associated to higher treatment related toxicity, loss of functional status, shorter progression free survival and overall survival in different types of cancer under various treatments. Hence, preservation of muscle mass and function should be an important focus of the multidisciplinary treatment of patients with LC. Pulmonary rehabilitation (PR) has been known to improve pulmonary function, reduce fatigue and improve exercise tolera

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📋 Eligibility rules (as published)
Inclusion Criteria: * Confirmed diagnosis of advanced non-small-cell lung cancer * Good performance status (ECOG 0-1) * Life expectancy \>12 weeks * Eligible to receive treatment with chemotherapy or tyrosinkinase inhibitors * Recent electrocardiogram without evidence of arrythmia Exclusion Criteria: * Symptomatic brain metastasis * Uncontrolled pain (Visual Analog Scale \>5) * Uncontrolled hypertension (\>140/100mmHg) * Practice of regular moderate to intense physical activity at least 3 day/week * Not residents of Mexico City or unable to attend to therapy sessions
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What it tests

  • Pulmonary rehabilitation
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Where

1 site
Instituto Nacional de Cancerología
Mexico City, Mexico
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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