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โ† Trials
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Cranial Nerves Tractography

RecruitingNAAges 18 Years - anyAllHospices Civils de Lyon
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In plain words

What the trial is, and whether it could suit you

Introduction: The skull base tumors surgery remains a challenge since numerous cranial nerves or vessels closely surround them. Recently, diffusion tensor imaging has developed with the tractography following white fibers and visualizing functional tracts. Cranial nerves tractography could allow predicting their displacement by skull base tumors that may help the surgeon to spare them along the surgery. Methods: Preoperative cerebral MRI was performed on patients who presented with skull base tumors. A 3 tesla MRI machine was used to acquire DTI sequence with specific parameters: 32 directions, slice thickness 2 mm, echo time 86 ms, repetition time 12000 ms, matrix 128x128, b-value 1000 s.mm-1. An anatomic sequence hyperT2 was overlaid as reference. Distortion was corrected by topup and eddy functions from FSL. Cranial nerves fibers were probabilistically tracked with Mrtrix3. Cranial n

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Patients who present a skull base tumor that requires surgical removal * Patients adult, informed and agreed Exclusion Criteria: * Pregnant women * Patients under 18 years old, unable to legally consent
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What it tests

  • preoperative cerebral MRI and operative findings
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Where

1 site
Service de Neurologie B, Hรดpital Neurologique, HCL
Bron, France
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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