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Blood Tests and Questionnaires in Studying Adherence to Preventative Swallowing Exercises in Participants With Metastatic Head and Neck Cancer

Recruitingn/aAges 18 Years - anyAllM.D. Anderson Cancer Center
NCT03010150 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This trial uses blood tests and questionnaires to study how well participants with head and neck cancer that has spread to other places in the body adhere to swallowing exercises to prevent future disease. Using blood tests to study cytokines (proteins related to the immune system) may help doctors learn if certain levels of cytokines affect whether or not side effects occur and if they put participants at risk for future disease. Questionnaires may help doctors learn about the reasons head and neck cancer participants may or may not follow the swallowing exercises that they are asked to perform after receiving radiation treatments.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Are dispositioned to receive radiation with curative intent for nasopharyngeal, oropharyngeal, hypopharyngeal, laryngeal, or an unknown primary cancer with cervical metastases * Are stage II-IVb for non- human papillomavirus (HPV)- related oropharyngeal cancer * Have HPV- related oropharynx cancer that is T1, have nodal involvement with no distant metastasis or have HPV- related oropharynx cancer that is at least T2 with no distant metastasis * Are stage II-IVb for laryngeal cancer * Are stage I-IVb for hypopharyngeal * Are stage I-IVb for nasopharyngeal cancer * Have stage I-III unknown primary cancer with cervical Exclusion Criteria: * Have other cancer diagnoses, except non-melanoma skin cancer * Had treatment for previous head and neck cancer or radiation to the head and neck * Have a history of previous head and neck surgery (excluding biopsy and/or tonsillectomy and/or tracheotomy) * Have a current oropharyngeal dysphagia unrelated to cancer diagnosis (e.g., dysphagia due to underlying neurogenic disorder)
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What it tests

  • Biospecimen Collection
  • Questionnaire Administration
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Where

1 site
M D Anderson Cancer Center
Houston, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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