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Corneal Elastography and Patient Specific Modeling

Recruitingn/aAges 16 Years - 80 YearsAllThe Cleveland Clinic
NCT03030755 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this research is to develop measurement tools and simulation technology for characterizing and predicting individual responses to corneal treatments and for advancing understanding of corneal ectasia risk factors. Patients who either 1) have keratoconus and are being evaluated for corneal crosslinking or 2) have refractive error and are being evaluated for refractive surgery procedures such as LASIK will have their eyes imaged to assess their mechanical properties and will have computational simulations performed to predict the response to treatment. One aim of the study is to test the hypothesis that computational models can predict the cornea's shape changes within clinically acceptable limits of error.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Any patient with keratoconus diagnosed by standard criteria, including topographic steepness, irregular astigmatism with a pattern consistent with keratoconus. * Any patient deemed a candidate for LASIK (laser vision correction) and scheduled for surgery. Exclusion Criteria: * Inability to provide informed consent, including non-English speaking (if interpreter not available) and cognitively/mentally impaired (if legal guardian not available).
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What it tests

  • Optical coherence tomography
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Where

1 site
Cleveland Clinic Foundation Cole Eye Institute
Cleveland, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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