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TMS for Complex Regional Pain Syndrome

RecruitingNAAges 18 Years - 70 YearsAllStanford University
NCT03137472 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of the current study is to assess the efficacy of TMS in the treatment of Complex Regional Pain Syndrome (CRPS). It is hypothesized that participants who receive TMS (Group 1) relative to sham treatment (Group 2) once daily for two days will demonstrate a greater improvement in CRPS-related pain and other associated symptomology (i.e., cognitive, emotional and physical) compared to baseline. Participants will be followed until they reach their baseline for two consecutive weeks to assess safety and duration of symptom alleviation.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18-70 * Diagnosis of CRPS (complex regional pain syndrome) for at least 3 months * Average pain level reported on Numerical Rating Scale meets entry criteria * Ability to perform the experimental task and procedures. Exclusion Criteria: * MRI contraindication (metal implants or devices, claustrophobia) * TMS Contraindication (eg metal implant or devices near the site of stimulation) * History of epilepsy * History of a psychological or psychiatric disorder that would interfere with study procedures, at the discretion of the researcher. * Neurologic illness that would interfere with brain integrity * Current medical condition or medication use that would interfere with study procedures or data integrity, at the discretion of the researcher. * Currently pregnant or planning to become pregnant. * On going legal action or disability claim.
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What it tests

  • Transcranial Magnetic Stimulation (TMS)
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Where

1 site
Stanford Pain Management Center
Redwood City, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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