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Research on the Early and Prognosis Diagnosis of Vascular Dementia

Recruitingn/aAges 65 Years - anyAllNational Taiwan University Hospital
NCT03152630 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Around 10% of stroke survivors develop dementia within 3 months after stroke and over 20% more stroke patients have dementia in the subsequent 3 years. Previous studies documented a close relationship between stroke and Alzheimer's disease (AD). There are, however, no reliable biomarkers to detect cognitive dysfunction and dementia among stroke patients or to predict the risks of vascular dementia (VD) and AD among patients with stroke. There is a clear need to identify novel mediators of cognitive dysfunction in stroke patients to provide insights into the pathogenesis, to tailor clinical care based on risks, and to develop new therapeutic strategies. While the expression of messenger RNAs (mRNAs) and microRNAs (miRNAs) account for only \~1% of all transcribed species, up to 90% of the mammalian genome is transcribed as long non-coding RNAs (lncRNAs), a heterogeneous group of non-codin

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📋 Eligibility rules (as published)
Inclusion Criteria: * age older than 20 years old * willing to sign ICF * report oneself disease * have Taiwanese ID * atherosclerotic vascular diseases, but with at least 1 CV risk factor \[DM, dyslipidemia or under lipid lowering therapy, hypertension, smoking, old (M\>45, F\>55 years), family history of premature CAD, obesity Exclusion Criteria: * not willing to sign ICF
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What it tests

  • Not listed
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Where

1 site
NTUH
Taipei, Taiwan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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