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Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions

RecruitingPhase 4Ages 18 Years - 70 YearsAllWeill Medical College of Cornell University
NCT03218137 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Unblinded, controlled, non-randomized, mechanistic study to determine whether physiological mechanisms underlying PVC are sensitive to adenosine. One hundred subjects undergoing clinically-indicated, standard-of-care cardiac electrophysiology study (EPS) procedure for PVCs will receive adenosine and/or verapamil to learn if their arrhythmias are inducible similarly to sustained ventricular tachycardia.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of premature ventricular contractions (PVCs) * Scheduled to undergo an electrophysiology study with the intention of performing cardiac ablation for the treatment of PVCs * Male or female between the ages of 18 and 70 years * Capable of giving informed consent Exclusion Criteria: * Any structural heart disease * Coronary artery disease (≥ 70% stenosis) * Current treatment with anti-arrhythmic drugs * Pregnant * Asthma (if administering adenosine)
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What it tests

  • Adenosine
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Where

1 site
Weill Cornell Medicine
New York, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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