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Prospective Endoscopic Follow-up of Patients With Submucosal and High Risk Mucosal Esophageal Adenocarcinoma

RecruitingNAAges 18 Years - anyAllAmsterdam UMC
NCT03222635 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Aim of this prospective multicenter study is to evaluate the safety of an endoscopic follow-up strategy in patients treated with endoscopic resection (ER) for submucosal or high-risk mucosal esophageal adenocarcinoma (T1bN0M0 or HR T1aN0M0 EAC).

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with submucosal or high-risk mucosal EAC diagnosed in an ER specimen, by an expert gastrointestinal (GI) pathologists. * Signed informed consent. Exclusion Criteria: * Prior history of high-risk mucosal or ≥T1sm. * Synchronous esophageal squamous cell carcinoma. * Suspicion on lymph node metastasis or distant metastasis on EUS, ultrasound of the neck or CT-thorax-abdomen performed six weeks after ER during baseline measurement. * Tumor-positive deep resection margin (R1) in ER specimen. * Patients unable to give signed informed consent.
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What it tests

  • Endoscopic follow-up
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Where

20 sites
Westmead hospital
Sydney, Australia
CUB Hôpital Erasme
Brussels, Belgium
AZ Maria Middelares Ghent
Ghent, Belgium
UZ Leuven
Leuven, Belgium
AZ Delta Roeselare
Roeselare, Belgium
Universitätsklinikum Augsburg
Augsburg, Germany
EVK Duesseldorf
Düsseldorf, Germany
MRI TUM
Münich, Germany

…and 12 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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