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Oxytocin and Fetal Heart Rate Changes

RecruitingPhase 4Ages 18 Years - 55 YearsFemaleUnyime Ituk
NCT03232918 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The reported risk of nonreassuring fetal heart trace following neuraxial analgesia is 3-23%. This variability may be due to fluid and oxytocin management prior to and during the initiation of neuraxial analgesia. The study hypothesis is that decreasing the oxytocin infusion rate by 50 % prior to initiation of combined spinal epidural analgesia will cause a reduction in the incidence of adverse fetal heart rate changes.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Healthy nulliparous or multiparous women at term (37 \> weeks' gestation) * Singleton pregnancy * Request for neuraxial analgesia * Oxytocin used for induction of labor or augmentation of labor per institutional protocols Exclusion Criteria: * Use of chronic analgesic medications * Prior administration of systemic opioid labor analgesia * Non-vertex presentation * Contraindication to neuraxial analgesia * Category 3 fetal heart rate tracing prior to the initiation of combined spinal epidural analgesia
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What it tests

  • Half dose Oxytocin
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Where

2 sites
University of Iowa Hospitals and Clinics
Iowa City, United States
Medical College of Wisconsin
Milwaukee, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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