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Retinal Imaging in Neurodegenerative Disease

Recruitingn/aAges 18 Years - anyAllDuke University
NCT03233646 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography (OCT) and OCT angiography (OCTA) as well as ultra-widefield (UWF) fundus photography to assess the structure and function of the retinal and choroidal microvasculature and structure in persons with mild cognitive impairment (MCI) and Alzheimer's Disease (AD), Parkinson's Disease (PD), or other neurodegenerative disease, diseases as outlined.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults with neurodegenerative disease ((MCI, PD, AD, FTD, DLB, ALS, MS, HD, TBI, concussion, PTSD and other neurodegenerations as well as Down Syndrome) * Adults without neurodegenerative disease Exclusion Criteria: * Inability to cooperate with or complete testing or other neurologic or age- related ocular conditions that would impact image acquisition. * Eyes that have had intraocular surgery, other than cataract surgery. If two eyes satisfy the inclusion criteria, both eyes will be included in the study. If one eye satisfies the inclusion criteria, the eye that qualifies will be included in the study.
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What it tests

  • Retinal and Choroidal Imaging
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Where

1 site
Duke University Medical Center
Durham, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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