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โ† Trials
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Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia

RecruitingPhase 1, Phase 2Ages 18 Years - 45 YearsAllUniversity of Calgary
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In plain words

What the trial is, and whether it could suit you

A prospective double blind, placebo-controlled, randomized cross-over trial to evaluate the effect of lowering cerebral blood flow on the ventilatory chemoreflexes (acute hypoxic and hypercapnic ventilatory responses).

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Healthy adults * 18 - 45 years of age * Living in Calgary for the past one year * Have no medical condition or should not be taking any blood pressure medications. * The participant should not be lactose intolerant Exclusion Criteria: * Cerebrovascular, cardio-respiratory, renal and metabolic diseases * Bleeding disorders and upper gastrointestinal diseases e.g. peptic ulcer disease * Pregnancy, obese and sleep-disordered breathing * Drug allergies to non-steroidal anti-inflammatories * Currently smoking
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What it tests

  • Drug Lowering Cerebral Blood Flow (CBF) and Normoxia Sleep
  • Drug Lowering CBF and Intermittent Hypoxia Sleep
  • Placebo and Normoxia Sleep
  • Placebo and Intermittent Hypoxia Sleep
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Where

1 site
University of Calgary
Calgary, Canada
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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