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โ† Trials
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Study of the Kono-S Anastomosis Versus the Side-to-side Functional End Anastomosis

RecruitingNAAges 18 Years - 90 YearsAllWeill Medical College of Cornell University
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In plain words

What the trial is, and whether it could suit you

This study proposes a randomized prospective study comparing the Kono-S anastomosis to the standard side-to-side anastomosis.This will be a multi-center randomized prospective trial. Patients with Crohn's ileitis or Crohn's ileocolitis requiring resection will be randomized to undergo either the Kono-S anastomosis or the side-to-side functional end anastomosis.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Patients with Crohn's ileitis or ileocolitis requiring initial surgical resection. 2. Age of 18 years and older, male and female 3. All Phenotypes of Crohn's diisease will be included: nonpenetrating (B1), stricturing (B2), and penetrating (fistulating) (B3), according to the Vienna classification 4. The patients can be on any medications coming into surgery, including prior anti- tumor necrosis factor(TNF) therapy. Exclusion Criteria: 1. Patients under 18 years of age 2. Patients with recurrent Crohn's 3. Pregnant patients 4. Patients with more than one non-contiguous site of active disease, thus requiring multiple resections or additional bowel sparing procedures at the time of surgery. 5. Patients with Crohn's disease extending to the cecum and ascending colon 6. Patients who will need preventive postoperative medical treatment 7. Patients that need change of surgical procedure as per the surgeon at the time of the intraoperative abdominal evaluation.
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What it tests

  • side-to-side functional end anastomosis
  • Kono-S analstomosis
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Where

15 sites
Massachusetts General Hospital
Boston, United States
Weill Cornell Medical College
New York, United States
University of Oklahoma
Oklahoma City, United States
Baylor Scott & White Research Institute
Dallas, United States
Baylor College of Medicine
Houston, United States
University of Washington Medical Center
Seattle, United States
University Clinics Gasthuisberg Herestraat
Leuven, Belgium
Helsinki University Hospital
Helsinki, Finland

โ€ฆand 7 more on ClinicalTrials.gov.

๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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