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Mirror Neuron Network Dysfunction as an Early Biomarker of Neurodevelopmental Disorder

Recruitingn/aAges 9 Months - 65 YearsAllEunice Kennedy Shriver National Institute of Chil…
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In plain words

What the trial is, and whether it could suit you

Background: People show changes in brain activity when they watch other people do actions. This may be part of early social and communication skills. Researchers want to understand the stages of normal development of motor observation and imitation in people and how it relates to social development in infants and toddlers. Objective: To study the nature of brain activity that underlies typical brain functioning in infants, toddlers, and adults. Eligibility: Infants ages 8 12 months Healthy adults ages 18 65 Design: Adult participants will have one visit. They will: Answer questions about their family, like its size and ethnicity. Answer questions about their own behavior and do a simple motor task. Have EEG/fNIRS. A damp elastic cap with small sensors will be placed on the head. Participants will observe stimuli, either on a video screen or of a live person. The sensors will b

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
* INCLUSION CRITIERIA: Healthy adults * Age of 18-65 at study entry * Healthy and good condition as determined by medical history and physical examination Healthy Infants * 9 months +/- 2 weeks of age at time of consent * Healthy and good condition as determined by medical history and physical examination * Age appropriate development as determined by parent report and exam * Full term at birth * Normal weight for gestational age At Risk Infants * 12 months +/- 2 weeks at the time of consent * Must have at least one of the following: observed developmental delay; sibling of a child with autism; premature birth; small for gestational age EXCLUSION CRITERIA: Healthy Adults * Uncorrected auditory impairment * Uncorrected visual impairment * Head injury with loss of consciousness * Inability to provide consent * Subject has a condition, that in the opinion of the investigator, creates an unacceptable risk for participation Healthy and At-Risk Infants * A language other than English as the primary language spoken at home * Having a medical impairment that interferes with study participation such as having a g-tube, shunt or seizure disorder and inability to hold one s head upright * Having a known visual impairment * Having a known auditory impairment
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What it tests

  • Not listed
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Where

1 site
National Institutes of Health Clinical Center
Bethesda, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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