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Metabolic Profile of Bone in Professional Athletes

Recruitingn/aAges 18 Years - anyAllI.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
NCT03386981 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Physical activity is a key stimulus for bone metabolism through both direct mechanisms (e.g., as a result of the applied load and/or impact) and indirect mechanisms (e.g., the activation of several metabolic pathways and the production of several mediators and effectors that have systemic effects). However, different kinds of physical activity exert different effects on bone and endocrine system. Aim of the study is to investigate the effects of different kinds of physical activity on bone metabolism and on the relationships existing between bone metabolism, energy metabolism, hormone profile, and organ functionality.

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📋 Eligibility rules (as published)
Inclusion Criteria: * \>/= 18 yo * healthy status * caucasians Exclusion Criteria: * \< 18 yo * pregnancy status * ongoing or previous (\<5 years) neoplasia * acute or chronic inflammatory pathologies * primary metabolic diseases of bone * recent bone fractures (\< 6 months) * chronic drugs * recent drugs administration (\< 2 months) for non steroidal anti-inflammatory drugs (NSAIDs) and steroids * anxious-depressive conditions * inability to understand the information given by the recruiting physician
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What it tests

  • blood and saliva tests
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Where

1 site
Istituto Ortopedico Galeazzi
Milan, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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