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Exercise Training in Patients With Persistent or Permanent Atrial Fibrillation

RecruitingNAAges 40 Years - anyAllOttawa Heart Institute Research Corporation
NCT03397602 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The main purpose of this project is to evaluate the effects of high-intensity interval training (HIIT) compared to moderate-intensity continuous exercise training (MICE) and standard care on exercise capacity and quality of life in patients with persistent or permanent atrial fibrillation. Positive findings are vitally important for these patients, given the condition's substantial morbidity, mortality and high economic costs.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. persistent or permanent atrial fibrillation; 2. rate controlled with a resting ventricular rate of equal to or less than 100 bpm; 3. able to perform a symptom-limited exercise test; 4. at least 40 years of age (i.e. participants must be 40 years or older); Exclusion Criteria: 1. currently participating in routine exercise training (more than two times per week); 2. unstable angina; 3. diagnosed severe mitral or aortic stenosis; 4. diagnosed hypertrophic obstructive cardiomyopathy with significant obstruction; 5. pregnant, lactating or planning to become pregnant during the study period; 6. unable to provide written, informed consent, or 7. unwilling or unable to return for follow up at week 12.
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What it tests

  • standard care + moderate-intensity continuous exercise training
  • standard care + high-intensity interval training
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Where

2 sites
London Health Sciences Network
London, Canada
University of Ottawa Heart Insititue
Ottawa, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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