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Patient Specific Biomechanical Modeling of Abdominal Aortic Aneurysm to Improve Aortic Endovascular Repair

RecruitingNAAges any - anyAllCentre hospitalier de l'Université de Montréal (C…
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In plain words

What the trial is, and whether it could suit you

This project is aiming at the integration of a biomechanical computer program with a guidance code to simulate the endovascular repair (EVAR) procedure of abdominal aortic aneurysm (AAA). The computational time associated with finite element simulation generally renders its usage impractical for real-time application. Based on data collected during clinical interventions and a priori knowledge of AAA and endovascular device mechanical modeling, the investigators are proposing a deformable registration between preoperative CT-scans and per-operative fluoroscopy that will take into account prior simulations of participant specific EVAR procedures. To avoid the computational cost of a full finite element simulation, the investigators propose a simplified and real-time compliant repetitive mechanical behaviour based on participant specific parameters. The results of this research will provi

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with a clinical indication for EVAR/FEVAR of AAA and meeting anatomic inclusion criteria on preoperative enhanced CT-scan compatible with an endovascular repair. * Willing and capable of providing informed consent Exclusion Criteria: * Contraindication to endovascular repair * Creatinine clearance \< 30ml/min * History of severe allergy to iodinated contrast (anaphylaxis, bronchospasm) * Absence of recent previous thin-slice enhanced CT-scanner examination (stent planning based on MRI examination or non-enhanced CT examination).
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What it tests

  • Biomechanical computer program
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Where

1 site
Centre Hospitalier de l'université de Montréal
Montreal, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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