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The Impact of Anti-thrombosis on Cerebral Microbleeds and Intracranial Hemorrhage in Ischemic Stroke Patients

Recruitingn/aAges 18 Years - anyAllGeneral Hospital of Shenyang Military Region
NCT03571763 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this prospective cohort study is to investigate whether antithrombotic therapy in the secondary prevention of ischemic stroke increases the risk of the emerging CMBs and whether the change is associated with an increased risk of intracranial hemorrhage, providing an imaging evidence for individualized antithrombotic therapy in such patients.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patient age ≥18 years; 2. Acute ischemic stroke patient confirmed by imaging; 3. Time of onset: within 3 months; 4. Baseline SWI sequence is completed before starting the secondary prevention of ischemic stroke; 5. Baseline SWI sequence must have at least one CMB ; 6. NIHSS≤10 Exclusion Criteria: 1. MRI contraindication; 2. Hemorrhagic transformation after acute Ischemic stroke; 3. Contraindication for antiplatelet or anticoagulation therapy; 4. Severe head trauma or intracranial hemorrhage occurred in the past six months; 5. obvious coagulopathy; 6. Other intracranial lesions associated with (such as tumor, cerebral vascular malformation); 7. other unqualified patients judged by the investigator
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What it tests

  • SWI sequence
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Where

1 site
General Hospital of ShenYang Military Region
Shenyang, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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