🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Targeted Blood-pressure Management and Acute Kidney Injury After Coronary Artery Bypass Surgery

RecruitingNAAges 50 Years - anyAllPeking University First Hospital
NCT03629418 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Acute renal injury (AKI) is a common complication after cardiac surgery and is associated with worse outcomes. It is now realized that intraoperative hypotension is an important risk factor for the development of AKI. In a recent randomized controlled trial of patients undergoing major noncardiac surgery, intraoperative individualized blood-pressure management reduced the incidence of postoperative organ dysfunction. The investigators hypothesize that, for patients undergoing off-pump CABG, targeted blood-pressure management during surgery may also reduce the incidence of postoperative AKI.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 50 years; * Scheduled to undergo off-pump CABG surgery. Exclusion Criteria: * Refuse to participate; * Untreated or uncontrolled severe hypertension (systolic blood pressure ≥180 mmHg or diastolic blood pressure ≥110 mmHg); * Chronic kidney disease with a glomerular filtration rate \< 30 ml/min/1.73 m2 or end-stage renal disease requiring renal-replacement therapy; * Inability to communicate during the preoperative period because of coma, profound dementia, language barrier, or end-stage disease; * Requirement of vasopressors/inotropics to maintain blood pressure before surgery; * Second or emergency surgery; * Expected survival of less than 24 hours.
💊

What it tests

  • Targeted blood-pressure management
  • Routine blood-pressure management
📍

Where

1 site
Beijing University First Hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy