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Innovative SolutIons for DosimEtry in Hadrontherapy (INSIDE)

Recruitingn/aAges 18 Years - anyAllCNAO National Center of Oncological Hadrontherapy
NCT03662373 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The study aim is to test the clinical feasibility and effectiveness of an online qualitative monitoring device named INSIDE system during hadrontherapy treatments. This instrumentation is composed by detectors able to acquire secondary signals generated by the interaction of the primary beam with human tissues. From these measurements performed during irradiation, the INSIDE system estimates the particle beam range inside the patient's body and check the compliance of the ongoing treatment with the clinical prescription, with the aim to optimize the delivered dose. The study aims to longitudinally monitor patients treated with hadrontherapy at the Italian National Centre of Oncological Hadrontherapy (CNAO) in Pavia in order to: * evaluate the stability of the INSIDE system response and the significance of the monitoring measurement; * study the clinical tolerances between ongoing and

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📋 Eligibility rules (as published)
Inclusion Criteria: * patients treated at CNAO with protons or carbon ions with horizontal beam line. * meningioma, ACC, skull base (clivus) chordoma, squamous cellular rhinopharynx carcinoma * full compatibility of the INSIDE monitoring system with all beam delivery devices in the established irradiating position * all emergency procedures are possible notwithstanding INSIDE system positioned. * signed written informed consent by patient. Exclusion Criteria * missing informed consent * not affected by one of the selected pathologies * failure of pre-treatment compatibility technical assessment * failure of pre-treatment emergency procedures check * medical or individual reasons (i.e. short time test needed)
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What it tests

  • carbon ions radiation therapy
  • protons radiation therapy
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Where

1 site
CNAO
Pavia, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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