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← Trials
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Diaphragm Structure and Pathobiology in Patients Being Bridged to Lung Transplant

Recruitingn/aAges 18 Years - anyAllUniversity Health Network, Toronto
NCT03667027 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is designed to characterize the changes in diaphragm structure, function and biology during bridging to lung transplant by mechanical ventilation or extracorporeal life support.

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📋 Eligibility rules (as published)
Inclusion Criteria (Cases): * Receiving a respiratory support modality as a bridge to lung transplantation * Formally listed for transplantation Inclusion Criteria (Control Group 1): \- Undergoing lung transplantation for either obstructive or restrictive lung disease Inclusion Criteria (Control Group 2): \- Undergoing elective thoracic surgery without any prior history of chronic pulmonary parenchymal disease Exclusion Criteria (Cases and Controls): * Previously diagnosed with neuromuscular disorder * Received invasive mechanical ventilation for \>48 hours in the preceding four weeks * Thoracic cage deformity
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What it tests

  • Respiratory support
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Where

1 site
Toronto General Hospital
Toronto, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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