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Comparison of Tumor Efficacy Safety in Laparoscopic Resection of Gastrointestinal Stromal Tumors Between Favorable and Unfavorable Site

Recruitingn/aAges 18 Years - 75 YearsAllFujian Medical University
NCT03716089 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Participants with gastrointestinal stromal tumors(GIST) were divided into favorable and unfavorable sites according to the anatomical site of the tumor, and this study aims to validate the overall postoperative morbidity and mortality rates between favorable site receiving laparoscopic resection of GIST and that of unfavorable site under the currently standard surgical therapy.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age between 18 and 75 years old 2. Primary gastric lesion confirmed pathologically GIST by endoscopic biopsy. Preoperative endoscopy, ultrasound endoscopy or computer tomography, Magnetic resonance suspected GIST, and then postoperative pathology confirmed as the original GIST 3. Written informed consent 4. Expected R0 resection by laparoscopy 5. Performance status of 0 or 1 on the ECOG (Eastern Cooperative Oncology Group) scale 6. ASA (American Society of Anesthesiology) class I to III 7. Maximum tumor diameter ≤10cm Exclusion Criteria: 1. Pregnant and lactating women 2. Suffering from a severe mental disorder 3. History of previous upper abdominal surgery (except for laparoscopic cholecystectomy) 4. History of previous gastric surgery (including ESD/EMR for gastric cancer) 5. Rejection of laparoscopic resection 6. History of other malignant disease within the past five years 7. History of unstable angina or myocardial infarction within the past six months 8. History of a cerebrovascular accident within the past six months 9. History of continuous systematic administration of corticosteroids within one month 10. Requirement of simultaneous surgery for another disease 11. Emergency surgery due to complications (bleeding, obstruction or perforation) caused by gastric cancer 12. FEV1\<50% of the predicted values 13. Maximum tumor diameter \>10cm
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What it tests

  • Laparoscopic resection
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Where

1 site
Fujian Medical University Union Hospital
Fuzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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