Prognostic Imaging Biomarkers for Diabetic Kidney Disease

Inclusion Criteria: * Diagnosis Diabetes Type 2; * eGFR \>= 30 ml/min/1.73m2; * Able to provide informed consent; * Age between 18 years and 80 years; * Unchanged antidiabetic and antihypertensive medication for the past 3 months (not including dose changes). Exclusion Criteria: * Transplantation (except corneal); * On permanent dialysis; * Significant comorbidities with life expectancy of \< 1 year; * Use of investigational drug within 1 month prior to screening; * Known clinical history of urinary obstruction on renal US: either post-voiding residue over 100 ml, or pyelectasis; * Known clinical history of aortic endoprosthesis at the renal level; * Current pregnancy; * History of Hepatitis B or Hepatitis C +; * Use of antiretroviral medication; * Known current or clinical history of renal or urinary tract malignancy; * Concurrent other renal disease (suspected or proven); * Cirrhotic liver disease, or non-cirrhotic chronic liver disease where ALT \>2 x upper limit of normal; * Current metastatic malignancy; * Current malignancy with expected survival \< study follow up period (4 years); * Melanomatous skin cancer \< 5 years ago (fully resected melanoma \>5 years ago, i.e. surgical cure, can be recruited); * Any other significant disease or disorder which, in the opinion of the investigators, may either put the patient at risk because of participation in the study, or may influence the result of the study, or the patient's ability to participate in the study; * Cochlear Implant; * Aneurysm Clips; * Neurological stimulator; * Implanted cardiac devices (ICD, PPM, loop recorders, or any others); * Metal heart valve; * History of metal foreign bodies in orbits; * Other implanted metal device which prevents MR imaging; * Known allergy to Gadolinium contrast; * Claustrophobia; * Weight exceeding 250 kg; * \[Bari arm\] Absolute contraindications to percutaneous renal biopsy; * \[Bari arm\] Bleeding diathesis; * \[Bari arm\] Severe uncontrolled hypertension; * \[Bari arm\] End stage renal disease with small hyperechoic kidneys;