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Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service

RecruitingNAAges 18 Years - 65 YearsAllHospital for Special Surgery, New York
NCT03747146 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

A comparison of two anesthetic techniques for total knee replacements: (1) Peri-Articular Injection (PAI), local infiltration between the popliteal artery and capsule of the knee block (IPACK) and single-shot adductor canal block (ACB) vs. (2) PAI, IPACK and continuous adductor canal block catheter (ACC).

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with osteoarthritis scheduled for a primary total knee arthroplasty with a participating surgeon * Planned use of regional anesthesia * Ability to follow study protocol * English speaking (secondary outcomes include questionnaires validated in English only) * Lives within one hour of the hospital * Has a smart phone Exclusion Criteria: * Hepatic or renal insufficiency * Younger than 18 years old or older than 65 years ol * Patients undergoing general anesthesia * Allergy or intolerance to one of the study medications * BMI \>40 * Diabetes * American Society of Anesthesiologists (ASA) status III or IV * Chronic gabapentin/pregabalin use (regular use for longer than 3 months) * Patients with chronic pain (from a referral to chronic pain service) or a pain catastrophizing scale (PCS \>30) * Patients with severe valgus deformity or flexion contracture * Patients unable to follow home catheter instructions and unwilling to go home with an infusing catheter * Patients who have no home caregivers in the event that a catheter is to be sent home with the patient * Patients with planned stay at rehab facility (to avoid medical device being tampered with at the rehab facility) * Non-English speakers (secondary outcomes include questionnaires validated in English only)
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What it tests

  • Continuous Adductor Canal Catheter (ACC)
  • Adductor Canal block with sham catheter
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Where

1 site
Hospital for Special Surgery
New York, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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