🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Collagen Cross-linking in Keratoconus

RecruitingNAAges 18 Years - anyAllOregon Health and Science University
NCT03760432 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Optical Coherence Tomography (OCT) devices are non-contact instruments that can measure the depth of scars, other causes of cloudiness of the cornea, and degree of corneal thinning in patients with keratoconus. Laser Custom Corneal Collagen Cross-linking (CXL) significantly decreases corneal aberrations and improves vision. This study will use OCT-guided setting for the lasers used in the corneal smoothing portion of the laser custom CXL procedure to assess the affect on visual outcomes.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of keratoconus * Minimum corneal thickness of 410 microns Exclusion Criteria: * Inability to maintain fixation for OCT imaging * Inability to commit to required study visits * Inability to give informed consent * Eyes with concurrent retinal diseases, glaucoma, or other eye conditions that may limit the visual outcome after surgery * Mature cataracts if found to limit visual potential to worse than 20/40
💊

What it tests

  • Laser Custom Corneal Collagen Cross-Linking
📍

Where

1 site
Oregon Health & Science University
Portland, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy