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Ischemic Postconditioning in STEMI Patients Treated With Primary PCI

RecruitingNAAges 18 Years - anyAllCopenhagen University Hospital, Rigshospitalet
NCT03787745 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In a prospective, randomized clinical trial the iPOST2 trial will determine whether ischemic postconditioning reduces reperfusion injury and this will translate into improved clinical outcome of heart failure and death for STEMI patients who present with TIMI0-1 undergoing primary PCI

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥18 years * Acute onset of chest pain with \< 12 hours duration * STEMI as characterized by 2 mm ST elevation in 2 or more V1 through V4 leads or presumed new left bundle branch block with minimum of 1 mm concordant ST elevation or 1 mV ST-segment elevation in the limb lead (II, III and aVF, I, aVL) and V4-V6 or ST depression in 2 or more V1 through V4 leads indicating posterior AMI. * TIMI flow 0-1 in infarct related artery Exclusion Criteria: * Potential pregnancy * Refusal to participate * OHCA without subsequent consciousness despite ROSC * Thrombectomy considered unavoidable
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What it tests

  • Ischemic postconditioning
  • Conventional
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Where

1 site
The Heart Center, Rigshospitalet, University of Copenhagen
Copenhagen, Denmark
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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