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Cessation of Long Term NAs vs. Keeping on NAs Among CHB Patients (CNAVK)

RecruitingPhase 4Ages any - anyAllHumanity & Health Medical Group Limited
NCT03792919 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

To Identify the collected cases who can stop NAs safely with satisfactory clinical outcome including sustain viral remission and HBsAg clearance among chronic hepatitis B(CHB) patients.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. HBsAg positive, HBeAg negative, antibody to HBeAg-positive; 2. Stable administration of anti-HBV neucleos(t)ides analogue mono therapy for at least more than one and a half year; 3. Demonstration of undetectable HBV DNA on three occasions, each at least 6 months apart, which is consistent with the APASL stopping rule; 4. Patients read, understand the consent form, and signed the study consent. Exclusion Criteria: 1. Patient with other liver diseases; 2. Patient with concurrent hepatitis viruses or HIV infection; 3. Patients are reluctant to stop their anti-HBV treatment.
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What it tests

  • Stop current treatment (anti-HBV neucleos(t)ides)
  • Keep current treatment (anti-HBV neucleos(t)ides)
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Where

1 site
Humanity & Health Research Centre
Hong Kong, Hong Kong
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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