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Metabolomics Study on Postoperative Intensive Care Acquired Muscle Weakness

Recruitingn/aAges 18 Years - anyAllTechnical University of Munich
NCT03810768 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In this mono-center pilot trial, surgical patients who are at high risk to be admitted to intensive care will be screened and asked for participation. We are going to take blood and muscle samples at respecified time points to do metabolic, histological and molecular testing. Aim of the study is to investigate (1) changes of the blood metabolome in patients with ICUAW (intensive care unit acquired weakness) and (2) identify metabolic components who are responsible for ICUAW or can be used as marker for ICUAW.

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📋 Eligibility rules (as published)
Inclusion Criteria: * invasive mechanically ventilated critically ill patient with expected intensive care unit stay \> 3 days * postoperative patient * ≥ 18 years old * American Society of Anesthesiology (ASA) classification ≥ III Exclusion Criteria: * moribund patient * non-curative care (comfort care)
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What it tests

  • Not listed
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Where

3 sites
Medical University of Vienna
Vienna, Austria
Klinikum rechts der Isar, School of Medicine, Technical University of Munich
Munich, Germany
Charité - Universitätsmedizin Berlin
Berlin, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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