Sex Differences in the Response to Abstinence From Alcohol.

Inclusion Criteria: * Moderate social drinkers * Able to understand/complete questionnaires and procedures in English * Body mass index (BMI) between 18.5 and 32 kg/m2 * Have venous access sufficient to allow blood sampling Exclusion Criteria: * Pregnant or breast-feeding women, or women who intend to become pregnant * Do not attest to using accepted forms of birth control for the infusion phase of the study * Current treatment for, or desire to be treated for, any substance use disorder or court ordered to not drink alcohol * History of significant adverse reaction to alcohol * Medical disorders or other conditions such as alcohol withdrawal seizures or delirium tremens that may influence study outcome or participant safety * Medications (past 30 days) that could influence data or participant safety (e.g. antidepressants, antipsychotics, benzodiazepines, etc.) as determined by investigators * DSM 5 Disorders (non AUD) or current/history of neurological disease of cerebral origin, or head injury with \> 20 min loss of consciousness * Positive breath alcohol reading on arrival at any study visit * Actively suicidal (for example, any suicide attempts within the past year or any current suicidal intent, including a plan) or are at serious suicidal risk, by clinical judgment of the investigator * Any condition for which the principal investigators determine it is unsafe or not prudent to enroll