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High Frame Rate Ultrasound in Heart Disease Assessment

Recruitingn/aAges 18 Years - anyAllLondon North West Healthcare NHS Trust
NCT03850015 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The study will compare standard ultrasound images to high frame rate ultrasound images in patients with heart disease or with a low risk of heart disease to see if a higher frame rate of ultrasound adds to the information obtained from standard ultrasound.

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📋 Eligibility rules (as published)
Inclusion criteria Either * Ability to give informed consent * age ≥18years and * confirmed inducible wall motion / perfusion abnormality on previous stress echocardiogram * known coronary artery disease - defined by presence of flow-limiting coronary stenosis(\>70% diameter stenosis) on coronary angiography. OR • patient who has been assessed as at low risk of having coronary heart disease Exclusion Criteria: * Inability to undertake pharmacological stress, ie previously known intolerance to dipyridamole; * Moderate or Severe aortic or mitral regurgitation or severe mitral stenosis; * Significant pulmonary disease like severe COPD or pulmonary fibrosis; * Atrial fibrillation; * Inability to provide informed consent; * Pregnancy and lactation; * Known allergy to Sonovue * Patients with second and third degree heart block, unless they have a pacemaker fitted * Systolic BP \< 90 * Known Myasthenia Gravis * Bronchial asthma
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What it tests

  • Standard echocardiography
  • High frame rate echocardiography
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Where

1 site
London North West University Healthcare NHS Trust
Harrow, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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