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Health Effects of the Standardized Research E-Cigarette in Smokers With HIV Smokers With HIV

RecruitingNAAges 18 Years - anyAllBrown University
NCT03862924 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Cigarette smoking is more prevalent (50-70%) in persons living with HIV in the U.S. when compared with the general population and is linked to increased rates of heart disease, lung diseases and infections, and lung cancers. Because of their high levels of nicotine dependence, low quit rates, and familiarity with harm reduction, HIV-positive smokers may view the use of alternative nicotine delivery products, such as electronic cigarettes (ECs), as an attractive option for reducing and eventually stopping combustible cigarette use. However, little is known about the health effects of electronic cigarette use in HIV-positive smokers. Some studies have shown that electronic cigarette use was associated with increased confidence to quit smoking in the general population. The primary objectives of this project are to examine whether HIV-positive smokers, who are unwilling or unable to quit sm

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📋 Eligibility rules (as published)
Inclusion Criteria: * diagnosed with and engaged in care for HIV (defined as at least one HIV clinic medical appointment within the past six month period) * at least 18 years of age * smoke at least 5 cigarettes per day for longer than one year * exhaled carbon monoxide (CO) level greater than 5 at BL Exclusion Criteria: * intention to quit smoking in the next 30 days * currently using pharmacotherapy for smoking cessation * currently using electronic cigarettes more than 2 days/week * unstable medical or psychiatric condition (defined as hospitalization) * medical contraindications to nicotine (unstable angina, uncontrolled hypertension, or recent cardiovascular event, including hospitalization) * psychotic symptoms * substance use disorder other than nicotine dependence * past-month suicidal ideation or past-year suicide attempt * pregnant or nursing.
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What it tests

  • Standardized Research Electronic Cigarette
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Where

1 site
Brown University School of Public Health
Providence, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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