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Sleep Related Memory Consolidation in Children With Age Related Focal Epilepsy.

RecruitingNAAges 6 Years - 13 YearsAllUniversity Hospital, Strasbourg, France
NCT03865771 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Age related focal epilepsies in children encompasses, according to the ILAE criteria, benign epilepsy with centro temporal spikes (BECTS), atypical benign partial epilepsy (ABPE) and epileptic encephalopathy with continuous spike and waves during sleep (ECSWS). These non structural epilepsies are associated with interictal sleep spike and waves activated by sleep. Moreover, high prevalence of learning disorders occur in children with age related epilepsies. A correlation is suspected between learning disorders and sleep activation of spike and waves. The investigators suppose that learning dysfunction is linked to loss of information during sleep of epileptic children, unlike for control patients. As sleep allows memory consolidation of words learned during wakefulness, an epileptic activity during sleep may disrupt this consolidation, leading to a loss of information. Hypothesis: the i

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📋 Eligibility rules (as published)
Inclusion Criteria: Principal: * normal psychomotor development * informed consent signed by both parents and subject if able * affiliated to social security regimen Specific Patients from "severe" and "benign" groups: * focal age related epilepsy: BECTS, ABPE, ECSWS (ILAE criteria) * children hospitalized for their follow-up * normal neuroimaging Control group -children hospitalized for a non neurologic disease Exclusion Criteria: Principal: Psychiatric trouble (DSM V) Sensorial trouble without correction Poor command of French language Minor under care Specific Patients from "severe" and "benign" groups: * degenerative disease * abnormal neuroimaging * mental deficiency Control group * neurologic trouble * abnormal sleep EEG * intellectual deficiency
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What it tests

  • Neuropsychological testing
  • Neuropsychological procedure
  • Video EEG and polysomnography
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Where

2 sites
Hopital D'Enfants Pediatrie Medicale Ambulatoire
Nancy, France
Hopital de Hautepierre-Service de Pediatrie/Neurologie
Strasbourg, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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