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Volume Support/Assist Control Mode Ventilation and Diaphragmatic Atrophy

RecruitingNAAges 18 Years - anyAllUniversity of Chicago
NCT03901924 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The objective of the study is to determine how controlled mode ventilation and support mode ventilation impact ventilator-free days and diaphragmatic atrophy.

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📋 Eligibility rules (as published)
Inclusion Criteria: subjects \> 18 years of age that have been intubated and mechanically ventilated for \< 36 hours at the time of screening will be eligible for enrollment Exclusion Criteria: 1. pregnancy 2. cardiopulmonary arrest 3. history of diaphragmatic paralysis or neuromuscular disease 4. chronic obstructive pulmonary disease (COPD) or asthma exacerbation with evidence of auto-PEEPing requiring intubation 5. neuromuscular blockade 6. expectation to be liberated from ventilator in \< 24 hours 7. history of mechanical ventilation in the last 6 months 8. presence of tracheostomy 9. high cervical spine injury
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What it tests

  • Volume Support Mode Mechanical Ventilation
  • Assist Control Mode Mechanical Ventilation
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Where

2 sites
The University of Chicago Medical Center
Chicago, United States
University of Iowa
Iowa City, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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