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Bupivacaine/Epinephrine +Dexamethasone vs. Liposomal Bupivacaine

RecruitingPhase 4Ages 18 Years - 90 YearsAllThe Cooper Health System
NCT03906617 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study will assess analgesia after robotic lung surgery. Subjects will be randomized to receive wound infiltration and intercostal nerve block with either liposomal bupivacaine or bupivacaine/epinephrine + dexamethasone. Liposomal bupivacaine is a newer local anesthetic product and has not been compared to a combination of bupivacaine/epinephrine + dexamethasone in the context of pain control after robotic lung surgery.

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📋 Eligibility rules (as published)
Inclusion Criteria: * undergoing robotic wedge resection or lobectomy for lung mass(es) Exclusion Criteria: * emergency case * history of opiate abuse * chronic pain syndrome * intravenous drug use * chronic use of oral steroids * pregnancy * imprisonment * body weight lower than 70 kg * liver failure * uninsured patients * non-verbal patients or patients who are unable to rate their pain on a visual analogue pain scale * history of allergic reaction to any of the drugs used in the study: bupivacaine, liposomal bupivacaine, dexamethasone
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What it tests

  • Intercostal nerve block and wound infiltration with liposomal bupivacaine
  • Intercostal nerve block and wound infiltration with bupivacaine/epinephrine + dexamethasone
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Where

1 site
Cooper University Hospital
Camden, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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