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Health and Exercise Response in Children With Chronic and Auto-immune Pathologies

RecruitingNAAges 6 Years - 18 YearsAllUniversity Hospital, Clermont-Ferrand
NCT03913962 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of the present project is to assess the effects of the chronic diseases and their associated treatments chronic paediatric diseases (CPD), to further understand their impact on physical fitness for public health perspectives. This is an innovative approach in the treatment of chronic paediatric diseases . This project should yield results that help improving treatments for children and adolescents with chronic paediatric diseases throughout physical activity as therapy, reduced pain, fatigue and inflammation, and improvement in physical fitness and life quality. The originality and novelty of this project is to combine architectural, functional and metabolic components of skeletal muscle to further understand the impact of chronic paediatric diseases as a function of treatment, disease activity and maturation status (prepubertal, pubertal or post pubertal). This study will aim a

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📋 Eligibility rules (as published)
Inclusion Criteria: * for patients: * Aged between 6 and 18-year-old * Male or female * Presenting a chronic pathology / having a treatment which is known to alter muscle mass and function, metabolism and body composition * Included in the active list of the hospital centre of Clermont-Ferrand * Free and informed consent of the holders of parental authority and the patient * Affiliated with the social security system for control: * Aged between 6 and 18-year-old * Male or female * Free and informed consent of the holders of parental authority and the patient * Affiliated with the social security system Exclusion Criteria: * for patients: * Treatment by systemic corticoids (\>1 week in the 30 days before test) * Contraindication to sport practice * Active infection for control: * Contraindication to sport practice * Chronic pathology susceptible to alter muscle mass and function, metabolism and body composition * Treatment susceptible to alter metabolism * Active infection
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What it tests

  • indirect calorimetry
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Where

1 site
Chu Clermont-Ferrand
Clermont-Ferrand, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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