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Metabolic Abnormalities, Lifestyle and Diet Pattern in Heart Failure

Recruitingn/aAges 14 Years - 90 YearsAllRuijin Hospital
NCT03951311 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Metabolic abnormalities (e.g., hypertension, diabetes mellitus, dyslipidemia, and obesity) and unhealthy lifestyle behaviors (e.g., smoking and drinking habits, sedentary behavior, sleep disorder and physical inactivity) and unhealthy diet (e.g., high sugar and high fat) are major risk factors for cardiovascular diseases mobility and mortality. The investigators sought to estimate the impact of metabolic abnormalities, lifestyle behavior and diet pattern on prognosis of heart failure. This study planned to consecutively enroll 1,500 participants with heart failure with reduced ejection fraction and heart failure with mid-range ejection fraction fulfilling the inclusion criteria. Each heart failure survivors will be followed up for 5 years. Information on metabolic diseases, lifestyle and diet pattern were obtained through standardized questionnaire. The major adverse cardiac events will

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. aged 14 years or older; 2. typical symptoms of heart failure according to the Framingham criteria; 3. left ventricular ejection fraction (LVEF) \<50%, demonstrated by echocardiography or cardiac magnetic resonance, which include either patients with mid-range EF (HFmEF) or with reduced EF (HFrEF) with relevant structural and functional cardiac changes and/or elevated N-terminal pro-brain B-type natriuretic peptide (pro-BNP) (e.g., ≥400 pg/mL). Exclusion Criteria: 1. age \<14 years or ≥90 years; 2. pregnancy; 3. cancer with a life expectancy of less than one year; 4. participation in other trials; 5. endocarditis, pericardial diseases, or congenital heart diseases; 6. heart failure secondary to non-cardiac diseases (e.g., pulmonary heart disease, infection, infiltration, metabolic derangements, severe anemia, sepsis, and arteriovenous fistula); 7. lack of informed consent; 8. refusal of the drug treatment or intervention recommended by the guidelines.
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What it tests

  • Not listed
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Where

1 site
Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Shanghai, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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