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Bowel Function/QoL After Elective Sigmoidectomy vs. Conservative Management for Recurrent Uncomplicated Diverticulitis

Recruitingn/aAges 18 Years - anyAllUniversity Hospital, Basel, Switzerland
NCT03994978 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The decision to perform a surgical intervention or not after recovery from repeated uncomplicated episodes of acute diverticulitis remains controversial and the literature shows different conflicting approaches based on low-quality evidence.The goal of this trial is to achieve a better understanding of the impact of surgery on bowel function and QoL in patients with recurrent uncomplicated sigmoid diverticulitis in order to develop treatment guidelines.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with recurrent uncomplicated diverticulitis and surgical indication for sigmoid resection * Patients with recurrent uncomplicated diverticulitis and non-surgical indication for conservative management * Confirmation of at least one episode of acute uncomplicated diverticulitis in computed tomography Exclusion Criteria: * Patients aged under 18. * Patients unable to understand an informed consent. * Patients with chronic pain disorder. * Patients with sigmoid fistulas * Emergency operations. * Pregnant women or lactation. * Patients with other severe gastrointestinal diseases, such as inflammatory bowel diseases (IBD), carcinoma or immunologic disorders. * Patients unable to perform surgery or high-risk patients according to the American Society of Anesthesiology (ASA 4 grade or higher)
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What it tests

  • elective sigmoidectomy
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Where

1 site
St. Claraspital Basel
Basel, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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