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Use of EBPT in Critically Ill Patients With AKI and/or Multiorgan Failure

Recruitingn/aAges any - anyAllCareggi Hospital
NCT04033224 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The use of extracorporeal blood purification therapies (EBPT) is becoming increasingly widespread worldwide in everyday clinical practice, particularly in the critical care setting. Nonetheless, most of the clinical trials aimed at exploring the effect of EBPT on patients' long-term outcomes have failed to demonstrate consistent results regarding 28 day- or hospital- mortality rates. The aim of this observational prospective registry is to evaluate if there is a cluster of critically ill patients that mostly benefits from extracorporeal blood purification therapies with different EBPTs.

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📋 Eligibility rules (as published)
Inclusion Criteria: * critically ill patients in the ICU * one of this EPB therapy: * CRRT/IHD/Hybrid therapies for support//replacement renal function * immunomodulation achieved by "high cut-off membranes", "endotoxins and/or cytokines adsorbent membranes" or by high-volume hemofiltration Exclusion Criteria: * patients treated only by Cytosorb® and/or Toraymyxin® therapies
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What it tests

  • Commercial membrane for Extracorporeal Blood Purification Therapy (EBPT)
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Where

15 sites
Ospedale S. Giuseppe
Empoli, Italy
Ospedale Versilia
Lido di Camaiore, Italy
Humanitas Research Hospital
Rozzano, Italy
IRCCS Policlinico S. Donato
San Donato Milanese, Italy
Ospedale S. Gerardo
Monza, Italy
Ospedale A. Perrino
Brindisi, Italy
Azienda Ospedaliero Universitaria Careggi
Florence, Italy
Fondazione IRCCS Policlinico San Matteo
Pavia, Italy

…and 7 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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