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Ozone Application Before Fissure Sealants

RecruitingNAAges 6 Years - 16 YearsAllIRCCS Burlo Garofolo
NCT04040920 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Decay is a multifactorial infective degenerative disease of hard dental tissues, caused by Streptococcus mutans and Lactobacillus forming the bacterial biofilm of teeth surfaces. Decays generally evolve in fissures and pits of secondary molars. Pits and fissure sealants prevent decays if performed in two years from eruption. Ozone has bactericidal effect and remineralizing capacity on enamel. The aim of this study is to assess the effectiveness of ozone application before sealants in increasing their duration in time.

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📋 Eligibility rules (as published)
Inclusion Criteria: * first or second secondary molars to be sealed * possibility to isolate with rubber dam both the teeth involved * no clear signs of pigmentations * good general health Exclusion Criteria: * latex allergy * epilepsy or other severe neurological pathologies * psychiatric disease * excessive sensibility to electrical current * severe asthma * enamel disorders, such as amelogenesis imperfect, white spots, fluorosis or Molar Incisors Hypomineralization
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What it tests

  • Ozone
  • Pits and fissure sealants
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Where

1 site
Institute for Maternal and Child Health - IRCCS Burlo Garofolo-
Trieste, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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